Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 4/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542581 | 0.91 | MAPKAPK2 (0.49) | MAPTKDM4ENPSR1MAPKAPK2MEN1 | |
| SCHEMBL11545991 | 0.89 | NAMPT (0.61) | KDM4EMEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL28845646 | 0.89 | RAD52 (0.56) | MAPTKDM4ENPSR1MAPKAPK2MEN1 | |
| SCHEMBL11542771 | 0.88 | NAMPT (0.48) | MAPTKDM4ENPSR1MAPKAPK2MEN1 | |
| SCHEMBL11544867 | 0.88 | NAMPT (0.62) | MAPTMAPKAPK2MEN1KMT2ANAMPT | |
| SCHEMBL11543456 | 0.87 | NAMPT (0.46) | MAPTKDM4ENPSR1MAPKAPK2MEN1 | |
| SCHEMBL11544535 | 0.87 | NAMPT (0.46) | MAPTKDM4ENPSR1MAPKAPK2MEN1 | |
| SCHEMBL11542080 | 0.87 | NAMPT (0.46) | MAPTKDM4ENPSR1MAPKAPK2MEN1 | |
| SCHEMBL11543979 | 0.86 | NAMPT (0.45) | MAPTKDM4ENPSR1MAPKAPK2MEN1 | |
| SCHEMBL11542231 | 0.86 | SLC6A7 (0.60) | KDM4EMAPKAPK2NAMPTCYP2C9PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |