Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 7/20 | 0.56 |
| ▸ | PPARA | Q07869 | 7/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TLR2 | O60603 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | FABP4 | P15090 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388402 | 1.00 | ADRA1A (0.57) | ADRA1AGPR84PPARGPPARDPPARA | |
| SCHEMBL11516867 | 1.00 | ADRA1A (0.57) | ADRA1AGPR84PPARGPPARDPPARA | |
| SCHEMBL31536450 | 1.00 | ADRA1A (0.57) | ADRA1AGPR84PPARGPPARDPPARA | |
| SCHEMBL28622058 | 1.00 | ADRA1A (0.57) | ADRA1AGPR84PPARGPPARDPPARA | |
| Azelaic Acid SCHEMBL11513754 | 1.00 | ADRA1A (0.57) | ADRA1AGPR84PPARGPPARDPPARA | |
| SCHEMBL21634549 | 1.00 | ADRA1A (0.57) | ADRA1AGPR84PPARGPPARDPPARA | |
| SCHEMBL9259807 | 1.00 | ADRA1A (0.57) | ADRA1AGPR84PPARGPPARDPPARA | |
| SCHEMBL2209285 | 1.00 | ADRA1A (0.57) | ADRA1AGPR84PPARGPPARDPPARA | |
| SCHEMBL172839 | 1.00 | ADRA1A (0.57) | ADRA1AGPR84PPARGPPARDPPARA | |
| Hydrochloric Acid SCHEMBL16059309 | 0.98 | ADRA1A (0.55) | ADRA1AGPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103172562-B | Trisubstituted amine compounds as inhibitors of cholesteryl ester transfer protein CETP | TANABE SEIYAKU CO | 2015-04-22 | — | — | CN | disclosed |
| CN-101374817-B | Trisubstituted amine compounds as inhibitors of cholesteryl ester transfer protein CETP | MITSUBISHI TANABE PHARMA CORP | 2014-07-30 | — | — | CN | disclosed |
| CN-103172562-A | Trisubstituted amine compounds as inhibitors of cholesteryl ester transfer protein CETP | TANABE SEIYAKU CO | 2013-06-26 | — | — | CN | disclosed |
| CN-101374817-A | Trisubstituted amine compounds as inhibitors of cholesteryl ester transfer protein CETP | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-02-25 | — | — | CN | disclosed |
| US-4165329-A | CARBOXYLATED UREA METAL SALTS | CHEVRON RESEARCH COMPANY (US) | 1979-08-21 | — | — | US | disclosed |