SCHEMBL2209285

SCHEMBL2209285

CCNCCCCCCC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A P35348 1/20 0.57
GPR84 Q9NQS5 7/20 0.56
PPARG P37231 7/20 0.56
PPARD Q03181 7/20 0.56
PPARA Q07869 7/20 0.56
HDAC11 Q96DB2 5/20 0.56
TSHR P16473 5/20 0.56
PTPN1 P18031 3/20 0.56
ALDH1A1 P00352 2/20 0.56
TLR2 O60603 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
FABP4 P15090 2/20 0.56
SLC22A6 Q4U2R8 1/20 0.56
SLC22A8 Q8TCC7 1/20 0.56
MEN1 O00255 1/20 0.56
ESR1 P03372 1/20 0.56
ALOX15 P16050 1/20 0.56
PDE4A P27815 1/20 0.56
KMT2A Q03164 1/20 0.56
PDE3A Q14432 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8388402 1.00 ADRA1A (0.57) ADRA1AGPR84PPARGPPARDPPARA
SCHEMBL11516867 1.00 ADRA1A (0.57) ADRA1AGPR84PPARGPPARDPPARA
SCHEMBL31536450 1.00 ADRA1A (0.57) ADRA1AGPR84PPARGPPARDPPARA
SCHEMBL28622058 1.00 ADRA1A (0.57) ADRA1AGPR84PPARGPPARDPPARA
Azelaic Acid SCHEMBL11513754 1.00 ADRA1A (0.57) ADRA1AGPR84PPARGPPARDPPARA
SCHEMBL21634549 1.00 ADRA1A (0.57) ADRA1AGPR84PPARGPPARDPPARA
SCHEMBL9259807 1.00 ADRA1A (0.57) ADRA1AGPR84PPARGPPARDPPARA
SCHEMBL172839 1.00 ADRA1A (0.57) ADRA1AGPR84PPARGPPARDPPARA
SCHEMBL11540844 1.00 ADRA1A (0.57) ADRA1AGPR84PPARGPPARDPPARA
Hydrochloric Acid SCHEMBL16059309 0.98 ADRA1A (0.55) ADRA1AGPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023168367-A1 QUINOLINE cGAS ANTAGONIST COMPOUNDS IMMUNESENSOR THERAPEUTICS, INC. (US) 2023-09-07 WO disclosed
US-20230167105-A1 BCL-2 PROTEIN INHIBITORS RECURIUM IP HOLDINGS, LLC 2023-06-01 US disclosed
EP-4107152-A1 BCL-2 PROTEIN INHIBITORS Recurium IP Holdings, LLC (US) 2022-12-28 EP disclosed
CN-115461335-A BCL-2 protein inhibitors 里科瑞尔姆IP控股有限责任公司 2022-12-09 CN disclosed
WO-2021222114-A1 BCL-2 PROTEIN INHIBITORS RECURIUM IP HOLDINGS, LLC (US) 2021-11-04 WO disclosed
CN-113387938-A Substituted pyrimidine compound, preparation method, intermediate and application thereof 上海科技大学 2021-09-14 CN disclosed
US-8815998-B2 Modified natural rubber, production process for the same and rubber composition and tire prepared by using the same BRIDGESTONE CORPORATION (JP) 2014-08-26 US disclosed
EP-2348055-B1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING MODIFIED NATURAL RUBBER, AND RUBBER COMPOSITION AND TIRE USING THE SAME BRIDGESTONE CORP (JP) 2014-02-12 EP disclosed
CN-102264768-B Modified natural rubber, method for producing same, and rubber composition and tire using same BRIDGESTONE CORP 2013-10-09 CN disclosed
CN-102264768-A Modified natural rubber, method for producing same, and rubber composition and tire using same 2011-11-30 CN disclosed
US-20110224365-A1 MODIFIED NATURAL RUBBER, PRODUCTION PROCESS FOR THE SAME AND RUBBER COMPOSITION AND TIRE PREPARED BY USING THE SAME BRIDGESTONE CORPORATION (JP) 2011-09-15 US disclosed
EP-2348055-A1 MODIFIED NATURAL RUBBER AND METHOD FOR PRODUCING MODIFIED NATURAL RUBBER, AND RUBBER COMPOSITION AND TIRE USING THE SAME Bridgestone Corporation (JP) 2011-07-27 EP disclosed
WO-2007088996-A1 TRISUBSTITUTED AMINE COMPOUNDS AS INHIBITORS OF -CHOLESTERYL ESTER TRANSFER PROTEIN CETP MITSUBISHI TANABE PHARMA CORPORATION (JP) 2007-08-09 WO disclosed
US-4212964-A FOR ADHESIVES PHILLIPS PETROLEUM COMPANY (US) 1980-07-15 US disclosed
US-4212965-A MOLDING MATERIAL, HOT MELT ADHESIVES, COATINGS PHILLIPS PETROLEUM COMPANY (US) 1980-07-15 US disclosed
US-4207411-A TENSILE STRENGTH, DUCTILITY, AND TOUGHNESS PHILLIPS PETROLEUM COMPANY (US) 1980-06-10 US disclosed
US-4172194-A Producing fiber grade polyamide from terephthalic acid and 5-methyl-1,9-nonanediamine PHILLIPS PETROLEUM COMPANY (US) 1979-10-23 US disclosed
US-4051087-A LAMINATES, ADHESIVES PHILLIPS PETROLEUM COMPANY (US) 1977-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167105-A1 BCL-2 PROTEIN INHIBITORS BCL2, BCL2L1, BCL2L2 ADRA1A 4683/4885GPR84 4588/4885PPARG 2556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.