SCHEMBL11540933

SCHEMBL11540933

CNc1ccc2sc(=O)[nH]c(=O)c2c1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CMA1 P23946 1/20 0.38
AR P10275 1/20 0.37
ALDH1A1 P00352 1/20 0.37
PKM P14618 1/20 0.37
PDE3B Q13370 5/20 0.36
PDE3A Q14432 5/20 0.36
PIM1 P11309 2/20 0.36
PIM2 Q9P1W9 2/20 0.36
TP53 P04637 1/20 0.35
AURKA O14965 1/20 0.35
MAPT P10636 1/20 0.35
KIF11 P52732 1/20 0.34
POLB P06746 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
PARP14 Q460N5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11540003 0.81 KDM4E (0.51) ALDH1A1MAPTPOLBSMN1; SMN2
SCHEMBL11539525 0.80 KIF11 (0.46) ARALDH1A1PIM1AURKAMAPT
SCHEMBL18180389 0.79 CMA1 (0.56) CMA1ARALDH1A1PKMPDE3B
SCHEMBL12361999 0.77 PDE3B (0.54) CMA1ALDH1A1PKMPDE3BPDE3A
SCHEMBL11542785 0.77 PIM1 (0.45) CMA1ALDH1A1PKMPDE3BPDE3A
SCHEMBL11538159 0.77 KIF11 (0.44) CMA1ALDH1A1PDE3BPDE3APIM1
SCHEMBL11538149 0.74 CMA1 (0.41) CMA1PDE3BPDE3APIM1PIM2
SCHEMBL11540248 0.74 POLB (0.44) CMA1ALDH1A1MAPTPOLB
SCHEMBL11543811 0.74 PARP1 (0.50) CMA1ARALDH1A1PDE3BPDE3A
SCHEMBL6238353 0.74 PIM1 (0.44) CMA1PIM1PIM2AURKAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4140532-A ORGANIC SILVER SALT, CATALYST, REDUCING AGENT, 2H-1,3-BENZOTHIAZIN-2,4(3H-)DIONE FUJI PHOTO FILM CO., LTD. (JP) 1979-02-20 US disclosed