SCHEMBL11540248

SCHEMBL11540248

O=c1[nH]c(=O)c2cc(F)ccc2s1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
KDM4E B2RXH2 2/20 0.41
CMA1 P23946 1/20 0.41
MPI P34949 3/20 0.40
PMM2 O15305 2/20 0.40
APOBEC3G Q9HC16 2/20 0.40
G6PD P11413 1/20 0.40
PGR P06401 2/20 0.39
DAO P14920 1/20 0.39
PARP1 P09874 4/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
HTT P42858 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
PHOSPHO1 Q8TCT1 1/20 0.38
TLR9 Q9NR96 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11542785 0.78 PIM1 (0.45) POLBALDH1A1LMNAMAPTKDM4E
SCHEMBL11538149 0.78 CMA1 (0.41) CMA1PGRPARP1
SCHEMBL6238353 0.78 PIM1 (0.44) LMNAMAPTCMA1GAA
SCHEMBL11543811 0.78 PARP1 (0.50) ALDH1A1MAPTCMA1PARP1
SCHEMBL3224706 0.77 CMA1 (0.61) POLBALDH1A1LMNAMAPTKDM4E
SCHEMBL30534236 0.77 CMA1 (0.61) POLBALDH1A1LMNAMAPTKDM4E
SCHEMBL6190639 0.75 POLB (0.56) POLBALDH1A1LMNAMAPTKDM4E
SCHEMBL11540933 0.74 CMA1 (0.38) POLBALDH1A1MAPTCMA1
SCHEMBL11538159 0.74 KIF11 (0.44) ALDH1A1CMA1PGRPARP1
SCHEMBL11538167 0.74 PARP1 (0.46) ALDH1A1KDM4EPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4140532-A ORGANIC SILVER SALT, CATALYST, REDUCING AGENT, 2H-1,3-BENZOTHIAZIN-2,4(3H-)DIONE FUJI PHOTO FILM CO., LTD. (JP) 1979-02-20 US claimed
US-4140532-A ORGANIC SILVER SALT, CATALYST, REDUCING AGENT, 2H-1,3-BENZOTHIAZIN-2,4(3H-)DIONE FUJI PHOTO FILM CO., LTD. (JP) 1979-02-20 US disclosed