Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11541710 | 0.93 | NPC1 (0.43) | NPC1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11540965 | 0.90 | NPC1 (0.43) | NPC1ALDH1A1RAB9ASMN1; SMN2NCEH1 | |
| SCHEMBL11542390 | 0.88 | ALDH1A1 (0.42) | NPC1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4649274 | 0.84 | NPC1 (0.47) | NPC1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11541788 | 0.83 | NPC1 (0.63) | NPC1ALDH1A1RAB9ASMN1; SMN2NCEH1 | |
| SCHEMBL11541708 | 0.80 | NPC1 (0.46) | NPC1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11546720 | 0.78 | CNR2 (0.38) | SMN1; SMN2KDM4EPOLBCNR1CNR2 | |
| SCHEMBL11541586 | 0.77 | ALDH1A1 (0.37) | ALDH1A1NCEH1 | |
| SCHEMBL7186178 | 0.77 | KDM4E (0.40) | NPC1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL123853 | 0.77 | NPC1 (0.51) | NPC1RAB9ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179548-A | UV curable resin compositions containing urethanes of hydroxybenzotriazoles or urethanes of hydroxy benzophenones | GENERAL ELECTRIC COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4061652-A | Urethanes of hydroxybenzotriazoles | GENERAL ELECTRIC COMPANY (US) | 1977-12-06 | — | — | US | disclosed |