SCHEMBL4649274

SCHEMBL4649274

C=C(C)C(=O)Oc1ccc(C(C)(C)CCCCC)cc1-n1nc2ccccc2n1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.47
RAB9A P51151 6/20 0.47
SMN1; SMN2 Q16637 5/20 0.47
ALDH1A1 P00352 4/20 0.47
MAPT P10636 5/20 0.41
KDM4E B2RXH2 3/20 0.41
HPGD P15428 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
CNR1 P21554 10/20 0.41
CNR2 P34972 10/20 0.41
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
POLB P06746 1/20 0.39
IGF2BP2 Q9Y6M1 1/20 0.36
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4253904 0.85 NPC1 (0.50) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL11541710 0.85 NPC1 (0.43) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL11540968 0.84 NPC1 (0.43) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL11542390 0.83 ALDH1A1 (0.42) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL226073 0.79 TSHR (0.35) NPC1RAB9ASMN1; SMN2ALDH1A1CNR1
SCHEMBL7186178 0.78 KDM4E (0.40) NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL123853 0.78 NPC1 (0.51) NPC1RAB9ACNR1CNR2
SCHEMBL11233663 0.78 CNR1 (0.39) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL2464346 0.77 CNR1 (0.52) NPC1RAB9ACNR1CNR2
SCHEMBL19328386 0.76 NPC1 (0.33) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8754167-B2 Actinic-light-curable composition, molded polycarbonate resin object with a cured film, and manufacturing method therefor KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2014-06-17 US disclosed
US-8742011-B2 Vehicle member and manufacturing method therefor KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2014-06-03 US disclosed
US-20130046053-A1 VEHICLE MEMBER AND MANUFACTURING METHOD THEREFOR KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2013-02-21 US disclosed
US-20130034735-A1 ACTINIC-LIGHT-CURABLE COMPOSITION, MOLDED POLYCARBONATE RESIN OBJECT WITH A CURED FILM, AND MANUFACTURING METHOD THEREFOR KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2013-02-07 US disclosed
EP-2546057-A1 VEHICLE MEMBER AND MANUFACTURING METHOD THEREFOR Kabushiki Kaisha Toyota Jidoshokki (JP) 2013-01-16 EP disclosed
EP-0931820-B1 Coating composition and its cured product JSR CORP (JP) 2008-03-19 EP disclosed
US-7229729-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method KONICA MONOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-06-12 US disclosed
US-20060040193-A1 Organic photoreceptor, image forming apparatus, image forming method and image forming unit KONICA MINOLTA HOLDINGS, INC. (JP) 2006-02-23 US disclosed
EP-1138732-B1 Coating composition and cured product JSR CORP (JP) 2005-08-31 EP disclosed
US-20050037274-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and image forming method KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2005-02-17 US disclosed
EP-0824127-B1 Water-type dispersion composition JSR CORP (JP) 2004-07-14 EP disclosed
US-20020051889-A1 Coating composition and cured product JSR CORPORATION (JP) 2002-05-02 US disclosed
EP-1138732-A2 Coating composition and cured product JSR Corporation (JP) 2001-10-04 EP disclosed
US-6214416-B1 STORAGE STABILITY; PRODUCES COATING FILMS WITH GOOD APPEARANCE, ADHESION, WEATHER RESISTANCE, HARDNESS JSR CORPORATION (JP) 2001-04-10 US disclosed
EP-0931820-A1 Coating composition and its cured product JSR Corporation (JP) 1999-07-28 EP disclosed
US-5905109-A HYDROLYSIS AND CONDENSATION TO FORM POLYMERS WITH CATALYSTS JSR CORPORATION (JP) 1999-05-18 US disclosed
EP-0824127-A2 Water-type dispersion composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-02-18 EP disclosed