Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.66 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.66 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | PTGFR | P43088 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11656327 | 0.88 | GPR84 (0.49) | GPR84FFAR1ALOX5TBXA2RPTGFR | |
| SCHEMBL5436849 | 0.84 | ACE2 (0.56) | GPR84FFAR1ALOX5TBXA2RPTGFR | |
| SCHEMBL11700162 | 0.84 | GPR84 (0.49) | GPR84FFAR1ALOX5FFAR4FAAH | |
| SCHEMBL11092071 | 0.82 | GPR84 (0.42) | GPR84FFAR1ALOX5TBXA2RPTGFR | |
| SCHEMBL525619 | 0.81 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL4757199 | 0.81 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL525377 | 0.81 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL525700 | 0.81 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL2933185 | 0.81 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL22842 | 0.81 | GPR84 (1.00) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1646134-A | Method and composition for treatment of ocular hypertension and glaucoma | SUCAMPO AG (CH) | 2005-07-27 | — | — | CN | disclosed |
| CN-1525861-A | Methods for treating ocular hypertension and glaucoma | ��������˹�����տ����� | 2004-09-01 | — | — | CN | disclosed |
| US-4180672-A | 2-Organothio-2-cyclopentenones, organothio-cyclopentanes derived therefrom | TEIJIN LIMITED (JP) | 1979-12-25 | — | — | US | disclosed |
| US-4046787-A | ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-4017534-A | BRONCHODILATION, ANTISECRETORY | AMERICAN CYANAMID COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3996263-A | ANTIULCER | SANKYO COMPANY LIMITED (JA) | 1976-12-07 | — | — | US | disclosed |
| US-3932472-A | INHIBITORS OF GASTRIC ACID SECRETION | AMERICAN CYANAMID COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932463-A | BRONCHODILATORS, GASTRIC ACID SECRETION INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1976-01-13 | — | — | US | disclosed |