Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11516206 | 0.84 | ALOX5 (0.38) | GPR84FFAR1ALOX5FFAR4 | |
| SCHEMBL11656327 | 0.83 | GPR84 (0.49) | GPR84FFAR1ALOX5PTGER2TBXA2R | |
| SCHEMBL11541198 | 0.82 | GPR84 (0.66) | GPR84FFAR1ALOX5PTGER2TBXA2R | |
| SCHEMBL1506633 | 0.80 | GPR84 (0.64) | GPR84FFAR1MAPTFFAR4 | |
| SCHEMBL1506632 | 0.80 | GPR84 (0.64) | GPR84FFAR1MAPTFFAR4 | |
| SCHEMBL5436849 | 0.74 | ACE2 (0.56) | GPR84FFAR1ALOX5PTGER2TBXA2R | |
| SCHEMBL8199605 | 0.73 | FFAR4 (0.59) | GPR84FFAR1ALOX5PTGER2TBXA2R | |
| SCHEMBL29559353 | 0.73 | EPHX1 (0.48) | ALOX5ALDH1A1 | |
| SCHEMBL28380195 | 0.73 | EPHX1 (0.48) | ALOX5ALDH1A1 | |
| SCHEMBL29385123 | 0.73 | EPHX1 (0.48) | ALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489092-A | Prostanoic acid derivatives and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-12-18 | — | — | US | disclosed |
| US-4359467-A | Prostanoic acid derivatives and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-11-16 | — | — | US | disclosed |
| US-4284646-A | Prostanoic acid derivatives and their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |