Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5072856 | 1.00 | LIPG (0.53) | LIPGNR1H2NR1H3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28853938 | 1.00 | LIPG (0.53) | LIPGNR1H2NR1H3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2898929 | 1.00 | LIPG (0.53) | LIPGNR1H2NR1H3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28880990 | 1.00 | LIPG (0.53) | LIPGNR1H2NR1H3MEN1KMT2A | |
| SCHEMBL2904403 | 0.98 | LIPG (0.55) | LIPGNR1H2NR1H3MEN1KMT2A | |
| Bromide SCHEMBL28345248 | 0.96 | LIPG (0.53) | LIPGNR1H2NR1H3MEN1KMT2A | |
| Iodide SCHEMBL27772284 | 0.96 | LIPG (0.53) | LIPGNR1H2NR1H3MEN1KMT2A | |
| Bromide SCHEMBL5904514 | 0.96 | LIPG (0.53) | LIPGNR1H2NR1H3MEN1KMT2A | |
| Bromide SCHEMBL28191376 | 0.96 | LIPG (0.53) | LIPGNR1H2NR1H3MEN1KMT2A | |
| Bromide SCHEMBL28190793 | 0.96 | LIPG (0.53) | LIPGNR1H2NR1H3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148738-A | ALKYL OR AROMATIC SULFIDE OR POLYSULFIDE, QUATERNARY AMMONIUM HALIDE | CHEVRON RESEARCH COMPANY (US) | 1979-04-10 | — | — | US | disclosed |