Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11549394 | 0.90 | SCN9A (0.35) | CRBNKCNH2UGT2B7PLGPLAU | |
| SCHEMBL11542347 | 0.79 | TP53 (0.40) | TP53CRBNMAPTALDH1A1 | |
| SCHEMBL11544625 | 0.77 | MAPT (0.36) | CRBNDDB1MAPTLMNAALDH1A1 | |
| SCHEMBL11550418 | 0.74 | KDM4E (0.40) | CRBNDDB1MAPTALDH1A1KDM4E | |
| SCHEMBL11545281 | 0.74 | KDM4E (0.41) | CRBNDDB1ALDH1A1GFERKDM4E | |
| SCHEMBL11546400 | 0.74 | TYMS (0.36) | TP53CRBNDDB1MAPTLMNA | |
| SCHEMBL11542948 | 0.74 | TP53 (0.41) | TP53CRBNMAPTALDH1A1HSD17B10 | |
| SCHEMBL32688313 | 0.74 | CRBN (0.44) | CRBNDDB1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL1713613 | 0.74 | CRBN (0.44) | CRBNDDB1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL19807936 | 0.72 | SMN1; SMN2 (0.41) | CRBNKCNH2DDB1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167569-A | ANTICOAGULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |