Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.32 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542183 | 0.90 | TP53 (0.34) | SCN9ACRBNKCNH2UGT2B7PLG | |
| SCHEMBL19807936 | 0.80 | SMN1; SMN2 (0.41) | CRBNKCNH2RPS6KA3 | |
| SCHEMBL11547038 | 0.79 | SLC2A1 (0.37) | SCN9ACRBNKCNH2RPS6KA3 | |
| SCHEMBL11544043 | 0.78 | DAPK3 (0.37) | CRBN | |
| SCHEMBL20595719 | 0.78 | CYP1A2 (0.39) | CRBN | |
| SCHEMBL11545281 | 0.74 | KDM4E (0.41) | CRBN | |
| SCHEMBL32688313 | 0.74 | CRBN (0.44) | CRBN | |
| SCHEMBL1713613 | 0.74 | CRBN (0.44) | CRBN | |
| SCHEMBL11541492 | 0.71 | CYP1A1 (0.39) | KCNH2 | |
| SCHEMBL11542347 | 0.71 | TP53 (0.40) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167569-A | ANTICOAGULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |