Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573356 | 0.83 | TSHR (0.37) | TSHRNFKB1CYP2C19APLNR | |
| SCHEMBL11177582 | 0.81 | TSHR (0.33) | TSHRNFKB1CYP2C19 | |
| SCHEMBL5889385 | 0.76 | TSHR (0.33) | TSHRNFKB1CYP2C19 | |
| SCHEMBL2623474 | 0.75 | — | — | |
| SCHEMBL11166056 | 0.75 | TSHR (0.34) | TSHRNFKB1CYP2C19 | |
| SCHEMBL11465614 | 0.74 | TSHR (0.32) | TSHRNFKB1CYP2C19 | |
| SCHEMBL11173645 | 0.74 | TSHR (0.32) | TSHRNFKB1CYP2C19 | |
| SCHEMBL25262962 | 0.73 | TSHR (0.31) | TSHRNFKB1CYP2C19 | |
| SCHEMBL5649672 | 0.73 | MEN1 (0.33) | TSHRNFKB1CYP2C19 | |
| SCHEMBL9497581 | 0.72 | TSHR (0.30) | TSHRNFKB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154722-A | PHOTOSTABILITY | CIBA-GEIGY CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |