Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573356 | 0.89 | TSHR (0.37) | TSHRNFKB1CYP2C19 | |
| SCHEMBL11173645 | 0.77 | TSHR (0.32) | TSHRNFKB1CYP2C19 | |
| SCHEMBL11543129 | 0.74 | TSHR (0.37) | TSHRNFKB1CYP2C19 | |
| SCHEMBL5465237 | 0.74 | GAA (0.39) | — | |
| SCHEMBL11465613 | 0.69 | GAA (0.45) | TSHR | |
| SCHEMBL11177582 | 0.69 | TSHR (0.33) | TSHRNFKB1CYP2C19 | |
| SCHEMBL11175645 | 0.69 | UBE2M (0.38) | — | |
| SCHEMBL5889385 | 0.68 | TSHR (0.33) | TSHRNFKB1CYP2C19 | |
| SCHEMBL11166056 | 0.67 | TSHR (0.34) | TSHRNFKB1CYP2C19 | |
| SCHEMBL11172522 | 0.67 | GUSB (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238613-A | IMPARTING PHOTOSTABILITY AND OXIDATION AND HEAT RESISTANCE TO PLASTICS | CIBA-GEIGY CORPORATION (US) | 1980-12-09 | — | — | US | disclosed |