SCHEMBL1154319

SCHEMBL1154319

CN1[CH]C=CN=C1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1154329 0.70
SCHEMBL2265241 0.60
SCHEMBL3238162 0.57
SCHEMBL29001118 0.49
SCHEMBL6562332 0.47
SCHEMBL9596236 0.43
SCHEMBL22983129 0.42
Water SCHEMBL37240 0.40
Butane SCHEMBL27724399 0.37 TSHR (0.33)
SCHEMBL14616529 0.37

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110039693-A1 Pyrimidylmethyl Sulfonamide Compounds BASF SE (DE) 2011-02-17 US claimed
EP-2252606-A1 PYRIMIDYLMETHYL SULFONAMIDE COMPOUNDS BASF SE (DE) 2010-11-24 EP claimed
WO-2009101079-A1 PYRIMIDYLMETHYL SULFONAMIDE COMPOUNDS BASF SE (DE) 2009-08-20 WO claimed
WO-2009101078-A1 PYRIMIDYLMETHYL SULFONAMIDE COMPOUNDS BASF SE (DE) 2009-08-20 WO claimed