⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5786620 | 0.74 | — | — | |
| SCHEMBL4228653 | 0.73 | — | — | |
| SCHEMBL5435524 | 0.68 | — | — | |
| SCHEMBL1154319 | 0.57 | — | — | |
| SCHEMBL6901232 | 0.51 | — | — | |
| SCHEMBL23047544 | 0.50 | — | — | |
| SCHEMBL6675567 | 0.47 | — | — | |
| SCHEMBL2047227 | 0.47 | — | — | |
| SCHEMBL2039629 | 0.47 | — | — | |
| SCHEMBL15214971 | 0.46 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210886-B1 | PYRIMIDYL INDOLINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2015-09-23 | — | — | EP | disclosed |
| US-8232287-B2 | Pyrimidyl indoline compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-07-31 | — | — | US | disclosed |
| US-20100292259-A1 | PYRIMIDYL INDOLINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-11-18 | — | — | US | disclosed |
| EP-2210886-A1 | PYRIMIDYL INDOLINE COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2010-07-28 | — | — | EP | disclosed |
| EP-0168730-B1 | PROCESS FOR FORMING DIRECT POSITIVE IMAGES, DIRECT POSITIVE SILVER HALIDE ELEMENTS, COMPOSITIONS AND COMPOUNDS AS CHARACTERISTIC FEATURE OF SUCH PROCESSES AND ELEMENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4988811-A | Developer autooxidation promoters for use in direct positive photography in silver halide emulsions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-01-29 | — | — | US | disclosed |
| US-4636457-A | Process for forming direct positive images, direct positive silver halide elements, compositions and compounds as characteristics feature of such processes and elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| EP-0168730-A2 | Process for forming direct positive images, direct positive silver halide elements, compositions and compounds as characteristic feature of such processes and elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-01-22 | — | — | EP | disclosed |