⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7054967 | 0.81 | GSK3A (0.30) | — | |
| SCHEMBL16578892 | 0.81 | — | — | |
| SCHEMBL25422566 | 0.78 | — | — | |
| SCHEMBL16625070 | 0.74 | GABRA1 (0.34) | — | |
| SCHEMBL25422711 | 0.69 | TDP1 (0.42) | — | |
| SCHEMBL12263871 | 0.61 | — | — | |
| SCHEMBL10066039 | 0.61 | — | — | |
| SCHEMBL16860627 | 0.61 | — | — | |
| SCHEMBL14506376 | 0.59 | ALDH1A1 (0.38) | — | |
| SCHEMBL348913 | 0.49 | AHR (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3087155-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | Albemarle Corporation (US) | 2016-11-02 | — | — | EP | disclosed |
| US-20160289527-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | ALBEMARLE CORP (US) | 2016-10-06 | — | — | US | disclosed |
| WO-2015100004-A1 | CONTROL OF SUSTAINED CASING PRESSURE IN WELLBORE ANNULI | ALBEMARLE CORPORATION (US) | 2015-07-02 | — | — | WO | disclosed |
| US-5215997-A | Synthesis of beta-lactam compounds | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| US-5153315-A | Penicilllin deriviatives | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4962196-A | (3S, 4R)-3,4-trans-disubstituted azetidin-2-one intermediates | CIBA-GEIGY CORPORATION (US) | 1990-10-09 | — | — | US | disclosed |