Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 5/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 2/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653246 | 0.82 | GBA1 (0.38) | — | |
| SCHEMBL11699801 | 0.79 | DGKA (0.54) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL11703150 | 0.79 | DGKA (0.54) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL11545321 | 0.77 | TSHR (0.40) | — | |
| SCHEMBL11618316 | 0.73 | DGKA (0.69) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL25243121 | 0.72 | DGKA (0.87) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL23042055 | 0.72 | DGKA (0.87) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL25245209 | 0.72 | DGKA (0.87) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL23041629 | 0.72 | DGKA (0.87) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL23041315 | 0.72 | DGKA (0.87) | DGKAPRSS1PRSS2PRSS3DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180672-A | 2-Organothio-2-cyclopentenones, organothio-cyclopentanes derived therefrom | TEIJIN LIMITED (JP) | 1979-12-25 | — | — | US | disclosed |