Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 3/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653246 | 0.94 | GBA1 (0.38) | TSHRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL11542464 | 0.91 | TSHR (0.36) | TSHRKMT2AALDH1A1LMNAKAT2B | |
| SCHEMBL11542784 | 0.86 | BRD4 (0.41) | TSHRALDH1A1MAPTHSD17B10 | |
| SCHEMBL12809274 | 0.85 | KDM1A (0.38) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL11541656 | 0.79 | LMNA (0.36) | TSHRKMT2AALDH1A1LMNAKAT2B | |
| SCHEMBL11543271 | 0.77 | DGKA (0.47) | — | |
| SCHEMBL11540280 | 0.76 | SOAT1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL11544425 | 0.74 | TSHR (0.38) | TSHRKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL11764316 | 0.74 | TSHR (0.44) | TSHRKMT2AALDH1A1LMNAKAT2B | |
| SCHEMBL11544721 | 0.73 | CYP4F2 (0.44) | KMT2AMEN1ALDH1A1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180672-A | 2-Organothio-2-cyclopentenones, organothio-cyclopentanes derived therefrom | TEIJIN LIMITED (JP) | 1979-12-25 | — | — | US | disclosed |