Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20499840 | 0.81 | TP53 (0.40) | TSHRALDH1A1TP53GLAAOC3 | |
| SCHEMBL20499845 | 0.79 | MAPT (0.36) | TSHRALDH1A1TP53GLAAOC3 | |
| SCHEMBL2271289 | 0.78 | TP53 (0.36) | TSHRALDH1A1TP53GLAAOC3 | |
| SCHEMBL3069583 | 0.74 | ESR1 (0.37) | TSHRALDH1A1AOC3HTR2AHRH1 | |
| SCHEMBL2276954 | 0.74 | ESR1 (0.37) | TSHRALDH1A1TP53AOC3HTR2A | |
| SCHEMBL10626373 | 0.71 | ESR1 (0.37) | TSHRALDH1A1TP53GLAAOC3 | |
| SCHEMBL11127633 | 0.70 | TSHR (0.34) | TSHRALDH1A1TP53GLAAOC3 | |
| SCHEMBL3889977 | 0.69 | TP53 (0.41) | TSHRALDH1A1TP53AOC3HTR2A | |
| SCHEMBL2100019 | 0.68 | TP53 (0.36) | TSHRALDH1A1TP53GLAAOC3 | |
| SCHEMBL2102622 | 0.68 | KCNH2 (0.39) | TSHRALDH1A1TP53GLAAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159267-A | Novel silyl ester azetidine-2-sulfenate intermediates and process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-3944545-A | Process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | disclosed |