SCHEMBL2271289

SCHEMBL2271289

CCN(CC)[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
GLA P06280 1/20 0.35
CHRM2 P08172 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
CHRM1 P11229 1/20 0.34
DRD1 P21728 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
ADRA1A P35348 1/20 0.34
OPRM1 P35372 1/20 0.34
DRD3 P35462 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KCNH2 Q12809 1/20 0.34
AOC3 Q16853 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2100019 0.80 TP53 (0.36) TP53TSHRALDH1A1GLACHRM2
SCHEMBL2102622 0.80 KCNH2 (0.39) TP53TSHRALDH1A1GLACHRM2
SCHEMBL9979418 0.80 TP53 (0.36) TP53TSHRALDH1A1GLACHRM2
SCHEMBL2272577 0.78 ESR1 (0.37) TP53TSHRALDH1A1GLACHRM2
SCHEMBL11543775 0.78 TSHR (0.36) TP53TSHRALDH1A1GLACHRM2
SCHEMBL2102653 0.78 ESR1 (0.37) TP53TSHRALDH1A1GLACHRM2
SCHEMBL10626373 0.78 ESR1 (0.37) TP53TSHRALDH1A1GLACHRM2
SCHEMBL10628245 0.78 TDP1 (0.43) OPRM1DRD3KCNH2
SCHEMBL2101242 0.76 ALDH1A1 (0.33) TP53TSHRALDH1A1GLACHRM2
SCHEMBL2101348 0.76 TP53 (0.33) TP53TSHRALDH1A1GLACHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250376758-A1 SELECTIVE DEPOSITION OF METAL-CONTAINING MATERIAL ASM IP HOLDING BV (NL) 2025-12-11 US disclosed
EP-1624851-B1 HAIR CARE APPLICATIONS OF EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES WITH NITROGEN ATOMS DOW CORNING (US) 2014-05-28 EP disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-7902293-B2 Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups DOW CORNING CORPORATION (US) 2011-03-08 US disclosed
CN-1791376-B Personal care applications of emulsions containing elastomeric silanes and siloxanes with nitrogen atoms DOW CORNING 2010-08-18 CN disclosed
CN-100445290-C Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups DOW CORNING (US) 2008-12-24 CN disclosed
EP-1625132-B1 METHOD OF PREPARING EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES HAVING QUATERNARY AMMONIUM GROUPS DOW CORNING (US) 2008-08-13 EP disclosed
US-20060269506-A1 Personal care applications of emulsions containing elastomeric silanes and siloxanes with nitrogen atoms DOW CORNING CORPORATION (US) 2006-11-30 US disclosed
US-20060193805-A1 Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups DOW SILICONES CORPORATION 2006-08-31 US disclosed
EP-1426398-B1 Method of making emulsion containing quaternary ammonium functional silanes and siloxanes DOW CORNING (US) 2006-07-05 EP disclosed
CN-1791605-A Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups DOW CORNING (US) 2006-06-21 CN disclosed
CN-1791376-A Personal care applications of emulsions containing elastomeric silanes and siloxanes with nitrogen atoms DOW CORNING (US) 2006-06-21 CN disclosed
EP-1624851-A1 PERSONAL CARE APPLICATIONS OF EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES WITH NITROGEN ATOMS Dow Corning Corporation (US) 2006-02-15 EP disclosed
EP-1625132-A1 METHOD OF PREPARING EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES HAVING QUATERNARY AMMONIUM GROUPS Dow Corning Corporation (US) 2006-02-15 EP disclosed
WO-2004103326-A1 PERSONAL CARE APPLICATIONS OF EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES WITH NITROGEN ATOMS DOW CORNING CORPORATION (US) 2004-12-02 WO disclosed
WO-2004104013-A1 METHOD OF PREPARING EMULSIONS CONTAINING ELASTOMERIC SILANES AND SILOXANES HAVING QUATERNARY AMMONIUM GROUPS DOW CORNING CORPORATION (US) 2004-12-02 WO disclosed
US-6787603-B2 REACTING EPOXIDE OR HALOHYDRIN DERIVATIZED NITROGEN ONIUM COMPOUND WITH AN AMINO FUNCTIONALIZED POLYSILOXANE IN WATER CONTAINING SURFACTANT DOW CORNING CORPORATION 2004-09-07 US disclosed
EP-1426398-A1 Method of making emulsion containing quaternary ammonium functional silanes and siloxanes DOW CORNING CORPORATION (US) 2004-06-09 EP disclosed
US-20040102570-A1 METHOD OF MAKING EMULSION CONTAINING QUATERNARY AMMONIUM FUNCTIONAL SILANES AND SILOXANES DOW SILICONES CORPORATION 2004-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060193805-A1 Method of preparing emulsions containing elastomeric silanes and siloxanes having quaternary ammonium groups COPE, ITCH, CUTA TP53 1162/4885TSHR 4691/4885ALDH1A1 3471/4885
US-20060269506-A1 Personal care applications of emulsions containing elastomeric silanes and siloxanes with nitrogen atoms CUTA, POLR1C, ITCH TP53 768/4885TSHR 4481/4885ALDH1A1 4144/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.