SCHEMBL11543782

SCHEMBL11543782

CCc1cc(C)c(C)cc1NC(=S)NC

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
MAPT P10636 2/20 0.49
LMNA P02545 2/20 0.40
ALOX12 P18054 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11515171 0.91 ALDH1A1 (0.47) ALDH1A1MAPTLMNAALOX12GAA
SCHEMBL11513102 0.79 ALDH1A1 (0.49) ALDH1A1MAPTLMNAALOX12GAA
SCHEMBL11512990 0.79 ALDH1A1 (0.61) ALDH1A1MAPTLMNAALOX12GAA
SCHEMBL11544764 0.76 ALDH1A1 (0.45) ALDH1A1MAPTLMNAALOX12GAA
SCHEMBL5452442 0.73 MAPT (0.72) ALDH1A1MAPTLMNAALOX12GAA
SCHEMBL11512360 0.72 ALDH1A1 (0.54) ALDH1A1MAPTLMNAALOX12GAA
SCHEMBL11542215 0.72 ALDH1A1 (0.53) ALDH1A1MAPTLMNAALOX12GAA
SCHEMBL11512492 0.71 ALDH1A1 (0.42) ALDH1A1MAPTLMNAALOX12GAA
SCHEMBL11541473 0.69 ALDH1A1 (0.54) ALDH1A1MAPTLMNAALOX12GAA
SCHEMBL11542475 0.69 ALDH1A1 (0.46) ALDH1A1MAPTLMNAALOX12GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4148799-A Process for the preparation of 2-aryliminothiazoline solutions BAYER AKTIENGESELLSCHAFT (DE) 1979-04-10 US disclosed