Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11513102 | 0.83 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTCYP1A2CYP2C19 | |
| SCHEMBL11512360 | 0.83 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTCYP1A2CYP3A4 | |
| SCHEMBL11423764 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1GAAMAPTPKMPLK1 | |
| SCHEMBL11137084 | 0.80 | GAA (0.43) | ALDH1A1GAAMAPTCYP1A2CYP3A4 | |
| SCHEMBL9313503 | 0.77 | KMT2A (0.49) | ALDH1A1GAAMAPTPKMLMNA | |
| SCHEMBL16386159 | 0.77 | RAB9A (0.47) | ALDH1A1MAPTLMNAHPGD | |
| SCHEMBL5452442 | 0.77 | MAPT (0.72) | ALDH1A1GAAMAPTCYP1A2CYP3A4 | |
| SCHEMBL11434640 | 0.77 | NPC1 (0.56) | ALDH1A1GAAMAPTCYP1A2CYP2C19 | |
| SCHEMBL9449596 | 0.76 | TRPA1 (0.40) | ALDH1A1GAAMAPTCYP1A2LMNA | |
| SCHEMBL11543782 | 0.76 | ALDH1A1 (0.49) | ALDH1A1GAAMAPTALOX12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |