Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546873 | 0.89 | MAPT (0.59) | TRPV1NPC1RAB9AFAAHMAPT | |
| SCHEMBL11545237 | 0.85 | TRPV1 (0.52) | TRPV1NPC1RAB9AFAAHMAPT | |
| SCHEMBL11544277 | 0.81 | MAPKAPK2 (0.56) | TRPV1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL11541220 | 0.79 | USP2 (0.53) | TRPV1FAAHMAPTSMN1; SMN2TSHR | |
| SCHEMBL11546870 | 0.78 | KDM4E (0.56) | TRPV1NPC1RAB9AMAPTKDM4E | |
| SCHEMBL11542583 | 0.78 | MAPT (0.42) | NPC1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11545449 | 0.76 | TRPV1 (0.52) | TRPV1FAAHMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11542846 | 0.75 | MEN1 (0.48) | NPC1MAPTSMN1; SMN2KDM4ETSHR | |
| SCHEMBL11730686 | 0.73 | MAPKAPK2 (0.52) | NPC1MAPTKDM4ETSHRALDH1A1 | |
| SCHEMBL28273734 | 0.73 | MEN1 (0.88) | NPC1RAB9AFAAHMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |