Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546870 | 0.91 | KDM4E (0.56) | MAPKAPK2MAPTPDGFRBNPSR1NPC1 | |
| SCHEMBL11545236 | 0.86 | MAPKAPK2 (0.56) | MAPKAPK2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11542855 | 0.86 | MAPKAPK2 (0.54) | MAPKAPK2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11544271 | 0.85 | MAPKAPK2 (0.56) | MAPKAPK2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11726280 | 0.84 | MAPKAPK2 (0.75) | MAPKAPK2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10838774 | 0.84 | MAPKAPK2 (0.61) | MAPKAPK2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11543764 | 0.84 | MAPKAPK2 (0.53) | MAPKAPK2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11812563 | 0.83 | RAD52 (0.64) | MAPKAPK2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11542636 | 0.83 | PDGFRB (0.53) | MAPKAPK2MAPTPDGFRBNPSR1KDM4E | |
| SCHEMBL11728397 | 0.83 | RAD52 (0.69) | MAPKAPK2MAPTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |