Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.49 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.49 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544280 | 0.85 | TRPV1 (0.60) | TRPV1POLBMAPTFAAHIGF1R | |
| SCHEMBL11545236 | 0.80 | MAPKAPK2 (0.56) | MAPTKMT2AMAPK1 | |
| SCHEMBL11542583 | 0.76 | MAPT (0.42) | MAPTIGF1RNPC1KMT2A | |
| SCHEMBL11545449 | 0.76 | TRPV1 (0.52) | TRPV1MAPTFAAHPRKAB2PRKAG1 | |
| SCHEMBL11542120 | 0.76 | PRKAB2 (0.54) | TRPV1MAPTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL11545277 | 0.76 | TRPV1 (0.58) | TRPV1MAPTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL11546873 | 0.76 | MAPT (0.59) | TRPV1MAPTFAAHPRKAB2PRKAG1 | |
| SCHEMBL11542846 | 0.76 | MEN1 (0.48) | MAPTNPC1KMT2A | |
| SCHEMBL11730686 | 0.74 | MAPKAPK2 (0.52) | POLBMAPTNPC1KMT2A | |
| SCHEMBL29263367 | 0.73 | POLB (0.58) | POLBMAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |