SCHEMBL1154434

SCHEMBL1154434

CCn1nnnc1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
POLB P06746 1/20 0.62
HTT P42858 1/20 0.62
P2RX7 Q99572 3/20 0.54
HSD11B1 P28845 2/20 0.54
KMT2A Q03164 2/20 0.50
TSHR P16473 2/20 0.50
MEN1 O00255 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HDAC6 Q9UBN7 1/20 0.48
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
LMNA P02545 1/20 0.45
HSD17B10 Q99714 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A4 P31645 1/20 0.45
SLC6A3 Q01959 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9603257 0.96 ALDH1A1 (0.58) ALDH1A1POLBHTTP2RX7HSD11B1
SCHEMBL4408289 0.85 ALDH1A1 (0.71) ALDH1A1POLBHTTP2RX7HSD11B1
SCHEMBL4409130 0.82 ALDH1A1 (0.64) ALDH1A1POLBHTTP2RX7HSD11B1
SCHEMBL6071045 0.81 ALDH1A1 (0.49) ALDH1A1POLBHTTP2RX7HSD11B1
SCHEMBL4513695 0.81 ALDH1A1 (0.53) ALDH1A1POLBHTTP2RX7HSD11B1
SCHEMBL4407364 0.81 ALDH1A1 (0.62) ALDH1A1POLBHTTP2RX7HSD11B1
SCHEMBL5651126 0.81 ALDH1A1 (0.62) ALDH1A1POLBHTTP2RX7HSD11B1
SCHEMBL12761225 0.81 ALDH1A1 (0.62) ALDH1A1POLBHTTP2RX7HSD11B1
SCHEMBL4403632 0.80 CNR2 (0.60) ALDH1A1POLBHTTP2RX7HSD11B1
SCHEMBL4407863 0.80 ALDH1A1 (0.57) ALDH1A1POLBHTTP2RX7HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9691951-B2 Curable silicone composition, and optical semiconductor device DOW CORNING TORAY CO., LTD. (JP) 2017-06-27 US claimed
EP-3059768-A1 CURABLE SILICONE COMPOSITION, AND OPTICAL SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2016-08-24 EP claimed
US-20160233395-A1 Curable Silicone Composition, And Optical Semiconductor Device DOW TORAY CO., LTD. (JP) 2016-08-11 US claimed
CN-1266201-C Foam cushion and method of making and using same PHAT CUSHION LLC (US) 2006-07-26 CN claimed
US-20050081980-A1 Foam cushion and method of making and using the same PHAT CUSHION LLC 2005-04-21 US claimed
CN-1511172-A Foam cushion and method of making and using same �����ι�˾ 2004-07-07 CN claimed
EP-1379578-A4 FOAM CUSHION AND METHOD OF MAKING AND USING THE SAME PHAT CUSHION LLC (US) 2004-05-12 EP claimed
EP-1379578-A1 FOAM CUSHION AND METHOD OF MAKING AND USING THE SAME Phat Cushion LLC (US) 2004-01-14 EP claimed
WO-2002068515-A1 FOAM CUSHION AND METHOD OF MAKING AND USING THE SAME PHAT CUSHION LLC (US) 2002-09-06 WO claimed
US-20020120024-A1 Foam cushion and method of making and using the same PHAT CUSHION LLC 2002-08-29 US claimed
EP-1231939-A2 ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER ELI LILLY AND COMPANY (US) 2002-08-21 EP claimed
EP-1231938-A2 ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER ELI LILLY AND COMPANY (US) 2002-08-21 EP claimed
WO-2001034197-A2 ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER ELI LILLY AND COMPANY (US) 2001-05-17 WO claimed
WO-2001034198-A2 ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER ELI LILLY AND COMPANY (US) 2001-05-17 WO claimed
WO-2001034135-A2 ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER ELI LILLY AND COMPANY (US) 2001-05-17 WO claimed
WO-2001034137-A2 ONCOLYTIC COMBINATIONS FOR THE TREATMENT OF CANCER ELI LILLY AND COMPANY (US) 2001-05-17 WO claimed
US-12441859-B2 Strain hardened polypropylene copolymer compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-10-14 US disclosed
EP-3649163-B1 POLYETHYLENE COMPOSITIONS COMPRISING CYCLIC-OLEFIN COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-08-07 EP disclosed
EP-0803530-A2 Cross-linked polyolefin tape Sentinel Products Corp. (US) 1997-10-29 EP disclosed
EP-0702032-A2 Cross-linked foam structures of essentially linear polyolefines and process for manufacture Sentinel Products Corp. (US) 1996-03-20 EP disclosed