Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1154434 | 0.96 | ALDH1A1 (0.62) | ALDH1A1POLBHTTP2RX7HSD11B1 | |
| SCHEMBL4513695 | 0.82 | ALDH1A1 (0.53) | ALDH1A1POLBHTTP2RX7HSD11B1 | |
| SCHEMBL4408289 | 0.82 | ALDH1A1 (0.71) | ALDH1A1POLBHTTP2RX7HSD11B1 | |
| SCHEMBL4409130 | 0.79 | ALDH1A1 (0.64) | ALDH1A1POLBHTTP2RX7HSD11B1 | |
| SCHEMBL6071045 | 0.79 | ALDH1A1 (0.49) | ALDH1A1POLBHTTP2RX7HSD11B1 | |
| SCHEMBL27565462 | 0.78 | ALDH1A1 (0.49) | ALDH1A1POLBHTTP2RX7MEN1 | |
| SCHEMBL4407364 | 0.78 | ALDH1A1 (0.62) | ALDH1A1POLBHTTP2RX7HSD11B1 | |
| SCHEMBL8947261 | 0.78 | ALDH1A1 (0.75) | ALDH1A1POLBHTTP2RX7HSD11B1 | |
| SCHEMBL5651126 | 0.78 | ALDH1A1 (0.62) | ALDH1A1POLBHTTP2RX7HSD11B1 | |
| SCHEMBL12761225 | 0.78 | ALDH1A1 (0.62) | ALDH1A1POLBHTTP2RX7HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210206-A | 1,3-oxazolyl substituted biphenyl | ABBOTT LABORATORIES (US) | 1993-05-11 | — | — | US | disclosed |