Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | GLI1 | P08151 | 1/20 | 0.36 |
| ▸ | GLI2 | P10070 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101149 | 0.82 | PTGS1 (0.49) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL24106552 | 0.80 | PTGS1 (0.57) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL7035268 | 0.80 | PTGS1 (0.57) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL31542598 | 0.80 | PTGS1 (0.57) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL15978566 | 0.80 | PTGS1 (0.57) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL11259635 | 0.79 | TLR4 (0.48) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL10866556 | 0.79 | PTGS1 (0.43) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL15977323 | 0.77 | PTGS1 (0.54) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL24106462 | 0.77 | PTGS1 (0.54) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL9664012 | 0.76 | ALOX5 (0.55) | PTGS1MEN1CYP2D6KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164415-A | Branched alkyl-2-naphthaleneacetic acids as herbicides and insecticide intermediates | AMERICAN CYANAMID CO. (US) | 1979-08-14 | — | — | US | disclosed |
| US-4088782-A | Substituted-benzyl α-C1 -C4 alkyl-2-naphthaleneacetates as insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4046799-A | INSECTICIDES | AMERICAN CYANAMID COMPANY (US) | 1977-09-06 | — | — | US | disclosed |