Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | EPOR | P19235 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10866556 | 0.91 | PTGS1 (0.43) | TLR4TLR2PTGS1ATMMEN1 | |
| SCHEMBL1101149 | 0.82 | PTGS1 (0.49) | TLR4TLR2PTGS1ATMMEN1 | |
| SCHEMBL11544353 | 0.79 | PTGS1 (0.50) | TLR4TLR2PTGS1ATMMEN1 | |
| SCHEMBL9664012 | 0.76 | ALOX5 (0.55) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL4449688 | 0.74 | PTGS1 (0.50) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL13886757 | 0.74 | PTGS1 (0.50) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL3857508 | 0.74 | ALDH1A1 (0.43) | PTGS1ATMMEN1KMT2ACYP2D6 | |
| SCHEMBL10867534 | 0.74 | TTR (0.35) | TLR4TLR2 | |
| SCHEMBL24106552 | 0.73 | PTGS1 (0.57) | PTGS1MEN1KMT2ACYP2D6ALOX5 | |
| SCHEMBL1677135 | 0.73 | TSHR (0.60) | PTGS1MEN1KMT2ACYP2D6ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003683-B1 | PROCESS FOR PREPARING HIGH CIS 3-(2,2,2-TRICHLOROETHYL)-2,2-DIMETHYLCYCLOPROPANE-1-CARBOXYLATES | FMC Corporation (US) | 1982-09-15 | — | — | EP | disclosed |