Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606905 | 0.80 | CASR (0.61) | L3MBTL1CASRKMT2AMEN1OPRK1 | |
| SCHEMBL11547536 | 0.79 | L3MBTL1 (0.50) | L3MBTL1CASRKMT2AMEN1OPRK1 | |
| SCHEMBL11542801 | 0.75 | L3MBTL1 (0.46) | L3MBTL1CASRKMT2AMEN1OPRK1 | |
| SCHEMBL11862638 | 0.74 | L3MBTL1 (0.51) | L3MBTL1CASRKMT2AMEN1OPRK1 | |
| SCHEMBL11606364 | 0.73 | L3MBTL1 (0.67) | L3MBTL1KMT2AMEN1OPRK1MAPT | |
| SCHEMBL13347118 | 0.70 | CASR (0.68) | CASRKMT2AMEN1 | |
| SCHEMBL11604828 | 0.70 | KMT2A (0.60) | L3MBTL1KMT2AMEN1OPRK1MAPT | |
| SCHEMBL11543572 | 0.70 | L3MBTL1 (0.48) | L3MBTL1KMT2AMEN1OPRK1MAPT | |
| SCHEMBL13347519 | 0.69 | CASR (0.67) | CASRKMT2AMEN1 | |
| SCHEMBL11469865 | 0.68 | L3MBTL1 (0.53) | L3MBTL1KMT2AMEN1OPRK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146717-A | NITROQUINAZOLINONE COMPOUNDS HAVING ANTIVIRAL PROPERTIES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-03-27 | — | — | US | disclosed |