Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 13/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13347118 | 0.88 | CASR (0.68) | CASRKMT2AMEN1 | |
| SCHEMBL13347519 | 0.86 | CASR (0.67) | CASRKMT2AMEN1 | |
| SCHEMBL11862638 | 0.85 | L3MBTL1 (0.51) | CASRKMT2AMEN1L3MBTL1NR1I2 | |
| SCHEMBL11547536 | 0.84 | L3MBTL1 (0.50) | CASRKMT2AMEN1L3MBTL1NR1I2 | |
| SCHEMBL11606364 | 0.84 | L3MBTL1 (0.67) | KMT2AMEN1L3MBTL1EGFROPRK1 | |
| SCHEMBL11604828 | 0.81 | KMT2A (0.60) | KMT2AMEN1L3MBTL1OPRK1MAPT | |
| SCHEMBL11544376 | 0.80 | L3MBTL1 (0.46) | CASRKMT2AMEN1L3MBTL1NR1I2 | |
| SCHEMBL11542801 | 0.80 | L3MBTL1 (0.46) | CASRKMT2AMEN1L3MBTL1NR1I2 | |
| SCHEMBL11601877 | 0.80 | CASR (0.67) | CASRNR1I2EGFRADRA2AADORA3 | |
| SCHEMBL7680445 | 0.79 | NR1I2 (0.72) | CASRKMT2ANR1I2EGFRADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4096144-A | Process for preparing quinazolinone derivatives and their 2-(N-mono-substituted amino)-phenyl ketone intermediate derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-06-20 | — | — | US | disclosed |
| US-4067868-A | Production of quinazolinone compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-01-10 | — | — | US | disclosed |
| US-3953446-A | Process for preparing quinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-27 | — | — | US | disclosed |