Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912488 | 0.75 | GAA (0.50) | LRRK2ALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL6189743 | 0.72 | HPGD (0.52) | LRRK2ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL17173944 | 0.71 | TSHR (0.46) | ALDH1A1KDM4EHTTMAPTTSHR | |
| SCHEMBL11704744 | 0.70 | MAPK8 (0.54) | LRRK2ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL5344963 | 0.70 | LMNA (0.51) | LRRK2ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL17173942 | 0.70 | LMNA (0.56) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL11544407 | 0.69 | MAPT (0.50) | ALDH1A1HPGDHTTMAPTTSHR | |
| SCHEMBL4029100 | 0.69 | ACHE (0.59) | ALDH1A1KDM4EHPGDHTTMAPT | |
| SCHEMBL6443545 | 0.69 | ADORA1 (0.63) | CHUK | |
| SCHEMBL12862579 | 0.68 | CA1 (0.52) | ALDH1A1KDM4EHPGDHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163846-A | HERBICIDES | FISONS LIMITED (GB) | 1979-08-07 | — | — | US | disclosed |