Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543689 | 0.90 | HTT (0.47) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL4288265 | 0.84 | ALDH1A1 (0.49) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL12702680 | 0.84 | ALDH1A1 (0.49) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL9871000 | 0.83 | HTT (0.49) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL11543554 | 0.78 | PAOX (0.51) | HTTALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL23309792 | 0.77 | HTT (0.43) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL21259228 | 0.77 | HTT (0.48) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL21755157 | 0.77 | HTT (0.48) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL20746932 | 0.77 | HTT (0.48) | HTTALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL19522401 | 0.77 | HTT (0.48) | HTTALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |
| US-4144256-A | FATTY AMIDE SUBSTITUTED WITH ACETYLTHIO GROUP OR GROUPS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1979-03-13 | — | — | US | disclosed |