Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 3/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288265 | 0.98 | ALDH1A1 (0.49) | HTTSMN1; SMN2ALDH1A1LMNAMGLL | |
| SCHEMBL12702680 | 0.98 | ALDH1A1 (0.49) | HTTSMN1; SMN2ALDH1A1LMNAMGLL | |
| SCHEMBL3608245 | 0.83 | SMN1; SMN2 (0.51) | HTTSMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL11543689 | 0.83 | HTT (0.47) | HTTSMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL11544900 | 0.83 | HTT (0.47) | HTTSMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL11543554 | 0.80 | PAOX (0.51) | HTTSMN1; SMN2ALDH1A1LMNAMGLL | |
| SCHEMBL6681364 | 0.78 | HTT (0.51) | HTTSMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL11228005 | 0.77 | MGLL (0.54) | HTTSMN1; SMN2ALDH1A1MGLLPDK1 | |
| SCHEMBL2718359 | 0.77 | L3MBTL1 (0.69) | HTTSMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL8972353 | 0.76 | L3MBTL1 (0.67) | SMN1; SMN2ALDH1A1LMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | claimed |
| US-5019611-A | Tetrahydrotriazinethiones | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0278890-A2 | Non-staining and slightly-staining antiozonants | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1988-08-17 | — | — | EP | disclosed |