Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1154492 | 1.00 | CA12 (0.40) | CA12CA2CA9CA1ADRA2A | |
| SCHEMBL12052186 | 1.00 | CA12 (0.40) | CA12CA2CA9CA1ADRA2A | |
| SCHEMBL12429824 | 0.86 | CA12 (0.39) | CA12CA2CA9CA1ADRA2A | |
| SCHEMBL1154049 | 0.85 | PABPC1 (0.35) | CA12CA2CA9PABPC1 | |
| SCHEMBL12052158 | 0.85 | PABPC1 (0.35) | CA12CA2CA9PABPC1 | |
| SCHEMBL1154051 | 0.85 | PABPC1 (0.35) | CA12CA2CA9PABPC1 | |
| SCHEMBL1154536 | 0.83 | CA2 (0.35) | CA12CA2CA9CA1PABPC1 | |
| SCHEMBL1154534 | 0.83 | CA2 (0.35) | CA12CA2CA9CA1PABPC1 | |
| SCHEMBL12052159 | 0.83 | CA2 (0.35) | CA12CA2CA9CA1PABPC1 | |
| SCHEMBL16330388 | 0.81 | CA1 (0.34) | CA2CA9CA1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8083809-B2 | Azomethine direct dyes or reduced precursors of these dyes obtained from 2-chloro-3-amino-6-methylphenol, and hair dyeing method starting from these dyes and precursors | L'OREAL S.A. (FR) | 2011-12-27 | — | — | US | claimed |
| EP-2229140-B1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-CHLORO-3-AMINO-6-METHYLPHENOL, AND HAIR DYEING METHOD STARTING FROM THESE DYES AND PRECURSORS | OREAL (FR) | 2011-08-03 | — | — | EP | claimed |
| US-20110041261-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-CHLORO-3-AMINO-6-METHYLPHENOL, AND HAIR DYEING METHOD STARTING FROM THESE DYES AND PRECURSORS | L'OREAL S.A (FR) | 2011-02-24 | — | — | US | claimed |
| US-8083809-B2 | Azomethine direct dyes or reduced precursors of these dyes obtained from 2-chloro-3-amino-6-methylphenol, and hair dyeing method starting from these dyes and precursors | L'OREAL S.A. (FR) | 2011-12-27 | — | — | US | disclosed |
| EP-2229140-B1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-CHLORO-3-AMINO-6-METHYLPHENOL, AND HAIR DYEING METHOD STARTING FROM THESE DYES AND PRECURSORS | OREAL (FR) | 2011-08-03 | — | — | EP | disclosed |
| US-20110041261-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-CHLORO-3-AMINO-6-METHYLPHENOL, AND HAIR DYEING METHOD STARTING FROM THESE DYES AND PRECURSORS | L'OREAL S.A (FR) | 2011-02-24 | — | — | US | disclosed |
| EP-2229140-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-CHLORO-3-AMINO-6-METHYLPHENOL, AND HAIR DYEING METHOD STARTING FROM THESE DYES AND PRECURSORS | L'Oréal (FR) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009077393-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-CHLORO-3-AMINO-6-METHYLPHENOL, AND HAIR DYEING METHOD STARTING FROM THESE DYES AND PRECURSORS | L'OREAL (FR) | 2009-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110041261-A1 | AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM 2-CHLORO-3-AMINO-6-METHYLPHENOL, AND HAIR DYEING METHOD STARTING FROM THESE DYES AND PRECURSORS | KRT18, MKI67, DNMT1 | CA12 401/4885CA2 737/4885CA9 739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.