Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8144828 | 0.81 | HSD17B10 (0.66) | HSD17B10POLBALDH1A1HPGDMAPK1 | |
| SCHEMBL8153543 | 0.79 | HSD17B10 (0.63) | HSD17B10POLBALDH1A1HPGDMAPK1 | |
| SCHEMBL6764561 | 0.78 | FFAR1 (0.61) | HSD17B10POLBALDH1A1HPGDMAPK1 | |
| SCHEMBL9661237 | 0.78 | HSD17B10 (1.00) | HSD17B10POLBALDH1A1HPGDMAPK1 | |
| SCHEMBL10508334 | 0.76 | HSD17B10 (0.59) | HSD17B10POLBALDH1A1HPGDMAPK1 | |
| SCHEMBL10504984 | 0.76 | HSD17B10 (0.59) | HSD17B10POLBALDH1A1HPGDMAPK1 | |
| SCHEMBL7963942 | 0.74 | HSD17B10 (0.61) | HSD17B10POLBALDH1A1HPGDMAPK1 | |
| SCHEMBL10807552 | 0.71 | HSD17B10 (0.50) | HSD17B10POLBALDH1A1HPGDMAPK1 | |
| SCHEMBL9642888 | 0.71 | HSD17B10 (0.50) | HSD17B10POLBALDH1A1HPGDMAPK1 | |
| SCHEMBL7977530 | 0.71 | HSD17B10 (0.54) | HSD17B10POLBALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152456-A | ANTIALLERGY, ANTIANAPHYLACTIC | AYERST, MCKENNA AND HARRISON LIMITED (CA) | 1979-05-01 | — | — | US | disclosed |
| US-4152457-A | ANTIALLERGY, ANTIANAPHYLACTIC | AYERST, MCKENNA AND HARRISON LIMITED (CA) | 1979-05-01 | — | — | US | disclosed |
| US-4110468-A | ANTIALLERGENS | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-08-29 | — | — | US | disclosed |
| US-4066784-A | ANTIALLERGINS | AYERST, MCKENNA AND HARRISON LTD. (CA) | 1978-01-03 | — | — | US | disclosed |