Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PRNP | P04156 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994239 | 0.83 | CYP1A2 (0.49) | HSD17B10POLBKMT2AHPGDALDH1A1 | |
| SCHEMBL8153543 | 0.80 | HSD17B10 (0.63) | HSD17B10POLBKMT2ARXFP1HPGD | |
| SCHEMBL7963942 | 0.79 | HSD17B10 (0.61) | HSD17B10POLBKMT2ARXFP1HPGD | |
| SCHEMBL10504984 | 0.74 | HSD17B10 (0.59) | HSD17B10POLBKMT2ARXFP1HPGD | |
| SCHEMBL7994077 | 0.74 | PDCD1 (0.46) | HSD17B10KMT2AHPGDALDH1A1MAPK1 | |
| SCHEMBL7997433 | 0.73 | ALDH1A1 (0.52) | HSD17B10POLBKMT2ARXFP1HPGD | |
| SCHEMBL7977633 | 0.73 | SMN1; SMN2 (0.56) | HSD17B10POLBKMT2AHPGDALDH1A1 | |
| SCHEMBL8144828 | 0.72 | HSD17B10 (0.66) | HSD17B10POLBKMT2ARXFP1HPGD | |
| SCHEMBL7975278 | 0.72 | PDCD1 (0.33) | HSD17B10ALDH1A1MAPK1KDM4EMAPT | |
| SCHEMBL11544945 | 0.71 | HSD17B10 (0.64) | HSD17B10POLBKMT2ARXFP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |