Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8179309 | 0.84 | CYP1A2 (0.69) | HSD17B10POLBCYP1A2RAB9ANPC1 | |
| SCHEMBL7977530 | 0.79 | HSD17B10 (0.54) | HSD17B10POLBKMT2ACYP1A2ALDH1A1 | |
| SCHEMBL8172677 | 0.79 | HSD17B10 (0.57) | HSD17B10POLBKMT2ACYP1A2RAB9A | |
| SCHEMBL8153543 | 0.77 | HSD17B10 (0.63) | HSD17B10POLBKMT2ACYP1A2ALDH1A1 | |
| SCHEMBL9661237 | 0.76 | HSD17B10 (1.00) | HSD17B10POLBKMT2ACYP1A2RAB9A | |
| SCHEMBL11544945 | 0.74 | HSD17B10 (0.64) | HSD17B10POLBKMT2ACYP1A2ALDH1A1 | |
| SCHEMBL2427544 | 0.73 | POLB (0.50) | HSD17B10POLBKMT2ACYP1A2RAB9A | |
| SCHEMBL23748605 | 0.73 | PTGS2 (0.50) | POLBCYP1A2RAB9ANPC1HSP90AA1 | |
| SCHEMBL4633858 | 0.73 | CYP1A2 (0.61) | HSD17B10POLBKMT2ACYP1A2RAB9A | |
| SCHEMBL8144828 | 0.72 | HSD17B10 (0.66) | HSD17B10POLBKMT2ACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |