Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 2/20 | 0.48 |
| ▸ | CFTR | P13569 | 6/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3471111 | 0.91 | L3MBTL1 (0.55) | L3MBTL1CFTRALOX5PTGS2OPRK1 | |
| SCHEMBL11550177 | 0.90 | L3MBTL1 (0.52) | L3MBTL1CFTRCYP19A1ALOX5PTGS2 | |
| SCHEMBL11548824 | 0.85 | L3MBTL1 (0.47) | L3MBTL1PDE5ACFTRCYP19A1ALOX5 | |
| SCHEMBL3472479 | 0.82 | CFTR (0.56) | L3MBTL1CFTRCYP19A1ALOX5PTGS2 | |
| SCHEMBL11604828 | 0.81 | KMT2A (0.60) | L3MBTL1CFTRCYP19A1OPRK1KMT2A | |
| SCHEMBL11159597 | 0.80 | L3MBTL1 (0.53) | L3MBTL1CFTRCYP19A1OPRK1KMT2A | |
| SCHEMBL11540068 | 0.80 | L3MBTL1 (0.50) | L3MBTL1CFTRALOX5PTGS2OPRK1 | |
| SCHEMBL11167732 | 0.79 | MAPT (0.61) | L3MBTL1CYP19A1OPRK1KMT2A | |
| SCHEMBL11160397 | 0.79 | L3MBTL1 (0.57) | L3MBTL1CFTRCYP19A1ALOX5PTGS2 | |
| SCHEMBL3469784 | 0.79 | CFTR (0.57) | L3MBTL1CFTRCYP19A1ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179432-A | 2-HYDROXYBENZOPHENONE, ORGANOTIN MERCAPTIDE PHOTOSTABILITY | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4146717-A | NITROQUINAZOLINONE COMPOUNDS HAVING ANTIVIRAL PROPERTIES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-03-27 | — | — | US | disclosed |