Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3472479 | 0.89 | CFTR (0.56) | L3MBTL1CFTRKMT2AOPRK1MAPT | |
| SCHEMBL11544946 | 0.85 | L3MBTL1 (0.48) | L3MBTL1CFTRKMT2AOPRK1CYP19A1 | |
| SCHEMBL11550177 | 0.85 | L3MBTL1 (0.52) | L3MBTL1CFTRKMT2AOPRK1MAPT | |
| SCHEMBL3471111 | 0.83 | L3MBTL1 (0.55) | L3MBTL1CFTRKMT2AOPRK1ALOX5 | |
| SCHEMBL11604828 | 0.80 | KMT2A (0.60) | L3MBTL1CFTRKMT2AOPRK1MAPT | |
| SCHEMBL11159597 | 0.79 | L3MBTL1 (0.53) | L3MBTL1CFTRKMT2AOPRK1MAPT | |
| SCHEMBL11540068 | 0.79 | L3MBTL1 (0.50) | L3MBTL1CFTRKMT2AOPRK1MAPT | |
| SCHEMBL11167732 | 0.78 | MAPT (0.61) | L3MBTL1KMT2AOPRK1MAPTHPGD | |
| SCHEMBL11160397 | 0.78 | L3MBTL1 (0.57) | L3MBTL1CFTRKMT2AOPRK1MAPT | |
| SCHEMBL3470351 | 0.78 | CFTR (0.57) | L3MBTL1CFTRKMT2AOPRK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146717-A | NITROQUINAZOLINONE COMPOUNDS HAVING ANTIVIRAL PROPERTIES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-03-27 | — | — | US | disclosed |