Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545113 | 1.00 | CHRM2 (0.47) | CHRM2CHRM4CHRM5KCNH2OPRK1 | |
| SCHEMBL30057981 | 0.84 | GRM6 (0.55) | CHRM2CHRM4CHRM5KCNH2OPRK1 | |
| SCHEMBL3155487 | 0.83 | OPRM1 (0.55) | CHRM2CHRM4CHRM5KCNH2OPRK1 | |
| SCHEMBL2841484 | 0.82 | CHRM2 (0.49) | CHRM2CHRM4CHRM5KCNH2OPRK1 | |
| SCHEMBL2841486 | 0.82 | CHRM2 (0.49) | CHRM2CHRM4CHRM5KCNH2OPRK1 | |
| SCHEMBL4477292 | 0.82 | CHRM2 (0.49) | CHRM2CHRM4CHRM5KCNH2OPRK1 | |
| SCHEMBL14086605 | 0.81 | CHRM2 (0.45) | CHRM2CHRM4CHRM5KCNH2OPRK1 | |
| SCHEMBL1513400 | 0.81 | DRD2 (0.62) | OPRK1OPRM1OPRD1DRD2DRD4 | |
| SCHEMBL4484205 | 0.79 | DRD2 (0.47) | CHRM2CHRM4CHRM5KCNH2OPRK1 | |
| SCHEMBL4479687 | 0.79 | CHRM2 (0.46) | CHRM2CHRM4CHRM5KCNH2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179567-A | 2-Aryltropane compounds | STERLING DRUG INC. (US) | 1979-12-18 | — | — | US | disclosed |