⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537211 | 0.83 | ELANE (0.39) | — | |
| SCHEMBL11363510 | 0.80 | TLR8 (0.44) | — | |
| SCHEMBL11535323 | 0.79 | ELANE (0.43) | — | |
| SCHEMBL11539993 | 0.77 | ELANE (0.44) | — | |
| SCHEMBL11543439 | 0.76 | HDAC4 (0.38) | — | |
| SCHEMBL11385099 | 0.75 | HDAC4 (0.34) | — | |
| SCHEMBL11537498 | 0.75 | — | — | |
| SCHEMBL11537071 | 0.74 | ELANE (0.40) | — | |
| SCHEMBL11538198 | 0.74 | HDAC4 (0.53) | — | |
| SCHEMBL8368027 | 0.72 | SMN1; SMN2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200216463-A1 | THAILANSTATIN ANALOGS | PH PHARMA CO., LTD. (KR) | 2020-07-09 | — | — | US | disclosed |
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |