Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11363510 | 0.89 | TLR8 (0.44) | ELANEKDM4ETLR8 | |
| SCHEMBL11535323 | 0.87 | ELANE (0.43) | ELANETLR8 | |
| SCHEMBL11539500 | 0.85 | DNM2 (0.44) | ELANETLR8MAPT | |
| SCHEMBL11545148 | 0.83 | — | — | |
| SCHEMBL11385099 | 0.79 | HDAC4 (0.34) | HDAC4MEF2DHSD11B1 | |
| SCHEMBL11542226 | 0.75 | ELANE (0.48) | ELANEHDAC4MEF2DKDM4ENPC1 | |
| SCHEMBL11539993 | 0.74 | ELANE (0.44) | ELANEHDAC4MEF2DHSD11B1 | |
| SCHEMBL11543439 | 0.73 | HDAC4 (0.38) | HDAC4MEF2DHSD11B1CA1CA2 | |
| SCHEMBL11537498 | 0.72 | — | — | |
| SCHEMBL11537071 | 0.71 | ELANE (0.40) | ELANEHDAC4MEF2DHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |