Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.43 |
| ▸ | DNM2 | P50570 | 7/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539500 | 0.98 | DNM2 (0.44) | ELANEDNM2TLR8ALDH1A1LMNA | |
| SCHEMBL11363510 | 0.95 | TLR8 (0.44) | ELANEDNM2TLR8ALDH1A1LMNA | |
| SCHEMBL11537211 | 0.87 | ELANE (0.39) | ELANETLR8 | |
| SCHEMBL21700132 | 0.76 | ELANE (0.43) | ELANEDNM2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11385099 | 0.75 | HDAC4 (0.34) | — | |
| SCHEMBL11538863 | 0.75 | NCF1 (0.41) | ALDH1A1LMNASMN1; SMN2KCNH3 | |
| SCHEMBL1527329 | 0.74 | ELANE (0.45) | ELANEALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11539161 | 0.72 | ELANE (0.38) | ELANETLR8 | |
| SCHEMBL11539177 | 0.72 | ELANE (0.38) | ELANETLR8KCNH3 | |
| SCHEMBL11544586 | 0.72 | LMNA (0.46) | ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |