Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545718 | 1.00 | MAOB (0.43) | MAOBNFE2L2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11546478 | 0.83 | CYP19A1 (0.46) | MAOBNFE2L2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL11546477 | 0.83 | CYP19A1 (0.46) | MAOBNFE2L2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5080527 | 0.79 | MAOA (0.56) | MAOBKDM4EMAPT | |
| SCHEMBL4725769 | 0.79 | MAOA (0.56) | MAOBKDM4EMAPT | |
| Phosphoric Acid SCHEMBL11548361 | 0.75 | KDM4E (0.60) | MAOBKDM4EMAPT | |
| Phosphoric Acid SCHEMBL11548364 | 0.75 | KDM4E (0.60) | MAOBKDM4EMAPT | |
| SCHEMBL5505859 | 0.72 | ALK (0.49) | MAOBNFE2L2MEN1KMT2AKDM4E | |
| SCHEMBL5505854 | 0.72 | ALK (0.49) | MAOBNFE2L2MEN1KMT2AKDM4E | |
| SCHEMBL8142080 | 0.71 | NFE2L2 (0.69) | MAOBNFE2L2CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |