Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL681204 | 0.81 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2TP53EPHX1 | |
| SCHEMBL11542469 | 0.77 | MEN1 (0.59) | KMT2AMEN1SMN1; SMN2TP53EPHX1 | |
| SCHEMBL1382899 | 0.74 | MEN1 (0.67) | KMT2AMEN1SMN1; SMN2TP53EPHX1 | |
| SCHEMBL10791571 | 0.74 | MEN1 (0.59) | KMT2AMEN1SMN1; SMN2TP53EPHX1 | |
| SCHEMBL30879612 | 0.74 | MEN1 (0.59) | KMT2AMEN1SMN1; SMN2TP53EPHX1 | |
| SCHEMBL8517158 | 0.72 | HSD17B10 (0.77) | KMT2AMEN1SMN1; SMN2TP53EPHX1 | |
| SCHEMBL2513794 | 0.71 | MEN1 (0.53) | KMT2AMEN1SMN1; SMN2TP53EPHX1 | |
| SCHEMBL5353973 | 0.71 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2TP53EPHX1 | |
| SCHEMBL4359332 | 0.71 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2TP53EPHX1 | |
| SCHEMBL11726723 | 0.71 | MEN1 (0.56) | KMT2AMEN1SMN1; SMN2TP53EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159267-A | Novel silyl ester azetidine-2-sulfenate intermediates and process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-3944545-A | Process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | disclosed |