SCHEMBL681204

SCHEMBL681204

C[Si](C)(C)N(C(=O)Nc1ccccc1)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
HSD17B10 Q99714 3/20 0.47
NAPRT Q6XQN6 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MTOR P42345 2/20 0.46
MAPT P10636 1/20 0.46
ALOX15 P16050 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
USP2 O75604 1/20 0.45
TP53 P04637 1/20 0.45
EPHX1 P07099 1/20 0.45
TSHR P16473 1/20 0.45
EPHX2 P34913 1/20 0.45
CDK9 P50750 1/20 0.45
CLK4 Q9HAZ1 1/20 0.45
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11742976 0.81 L3MBTL1 (0.40) MEN1KMT2AHSD17B10SMN1; SMN2NPC1
SCHEMBL11542469 0.81 MEN1 (0.59) MEN1KMT2AHSD17B10NAPRTSMN1; SMN2
SCHEMBL11545268 0.81 KMT2A (0.50) MEN1KMT2AHSD17B10NAPRTSMN1; SMN2
SCHEMBL27979600 0.80 KMT2A (0.38) MEN1KMT2AHSD17B10NAPRTSMN1; SMN2
SCHEMBL7938546 0.77 NPSR1 (0.50) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL2512409 0.76 MLYCD (0.65) MEN1KMT2AHSD17B10NAPRTSMN1; SMN2
SCHEMBL10791571 0.75 MEN1 (0.59) MEN1KMT2AHSD17B10NAPRTSMN1; SMN2
SCHEMBL1382899 0.75 MEN1 (0.67) MEN1KMT2AHSD17B10NAPRTSMN1; SMN2
SCHEMBL30879612 0.75 MEN1 (0.59) MEN1KMT2AHSD17B10NAPRTSMN1; SMN2
SCHEMBL8387202 0.75 NPSR1 (0.43) MEN1KMT2ASMN1; SMN2NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118667062-A Organosilicon modified methyl methacrylate crosslinked polymer, bulk polymerization method and application thereof 中国石油化工股份有限公司 2024-09-20 CN claimed
EP-0336428-B1 CURABLE COMPOSITION NIPPON PAINT CO., LTD. (JP) 1992-04-22 EP claimed
US-4983715-A FROM CARBOXYLIC ANHYDRIDE AND AMINE NIPPON PAINT CO., LTD. (JP) 1991-01-08 US claimed
EP-0184567-B1 PROCESS FOR THE FORMATION OF NEGATIVE PATTERNS IN A PHOTORESIST LAYER UCB Electronics, S.A. (BE) 1989-12-13 EP claimed
EP-0336428-A2 Curable composition NIPPON PAINT CO., LTD. (JP) 1989-10-11 EP claimed
EP-0184567-A1 Process for the formation of negative patterns in a photoresist layer UCB Electronics, S.A. (BE) 1986-06-11 EP claimed
US-4014873-A Process for the production of 7-acylamidocephalosporins MERCK & CO., INC. (US) 1977-03-29 US claimed
US-3944545-A Process for preparing desacetoxycephalosporins ELI LILLY AND COMPANY (US) 1976-03-16 US claimed
CN-118667062-A Organosilicon modified methyl methacrylate crosslinked polymer, bulk polymerization method and application thereof 中国石油化工股份有限公司 2024-09-20 CN disclosed
US-8067498-B2 Transparent curable polymer; one package process; high strength, elongation, weatherproofing, adhesive; blend containing vinyl living polymer, containing crosslinkable silicon groups, graft polymer containing rubber and acrylic ester with vinyl monomer and silica filler KANEKA CORPORATION (JP) 2011-11-29 US disclosed
US-7807746-B2 Curable composition KANEKA CORPORATION (JP) 2010-10-05 US disclosed
US-20100227949-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2010-09-09 US disclosed
US-20100222449-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2010-09-02 US disclosed
US-20100105798-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2010-04-29 US disclosed
US-4400509-A WITH HEXAMETHYLDISILANE WITH AN ORGANONITROGEN CATALYST GIST-BROCADES N.V. (NL) 1983-08-23 US disclosed
US-4159267-A Novel silyl ester azetidine-2-sulfenate intermediates and process for preparing desacetoxycephalosporins ELI LILLY AND COMPANY (US) 1979-06-26 US disclosed
US-4107432-A ANTIBIOTICS MERCK & CO., INC. (US) 1978-08-15 US disclosed
US-4058661-A 7-Diacyl cephalosporins MERCK & CO., INC. (US) 1977-11-15 US disclosed
US-4014873-A Process for the production of 7-acylamidocephalosporins MERCK & CO., INC. (US) 1977-03-29 US disclosed
US-3944545-A Process for preparing desacetoxycephalosporins ELI LILLY AND COMPANY (US) 1976-03-16 US disclosed