Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545515 | 0.90 | LMNA (0.47) | LMNASMN1; SMN2 | |
| SCHEMBL11553863 | 0.87 | LMNA (0.58) | LMNASMN1; SMN2 | |
| SCHEMBL11545664 | 0.85 | LMNA (0.52) | LMNASMN1; SMN2TSHRMAPK1 | |
| SCHEMBL11545272 | 0.84 | LMNA (0.31) | LMNA | |
| SCHEMBL11521895 | 0.78 | LMNA (0.51) | LMNASMN1; SMN2TSHRMAPK1 | |
| SCHEMBL11545562 | 0.78 | LMNA (0.41) | LMNATSHRMAPK1 | |
| SCHEMBL8752140 | 0.78 | LMNA (0.67) | LMNASMN1; SMN2TSHRMAPK1 | |
| SCHEMBL11547072 | 0.78 | LMNA (0.56) | LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8089018 | 0.76 | LMNA (0.65) | LMNASMN1; SMN2TSHRMAPK1 | |
| Iothalamic Acid SCHEMBL38419 | 0.75 | LMNA (0.56) | LMNASMN1; SMN2TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138589-A | CHEMICAL INTERMEDIATES FOR COMPOUNDS USED AS X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4069250-A | X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1978-01-17 | — | — | US | disclosed |