Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545376 | 0.86 | LMNA (0.46) | LMNAMAPK1TSHRHTTKDM4C | |
| Ammonia Solution, Strong SCHEMBL11547117 | 0.85 | LMNA (0.45) | LMNAMAPK1TSHRHTTKDM4C | |
| SCHEMBL4311751 | 0.81 | LMNA (0.47) | LMNAMAPK1TSHRHTTKDM4C | |
| SCHEMBL11522281 | 0.80 | LMNA (0.45) | LMNAMAPK1TSHRHTTKDM4C | |
| Hydrochloric Acid SCHEMBL1020768 | 0.80 | LMNA (0.46) | LMNAMAPK1TSHRHTTKDM4C | |
| SCHEMBL11406813 | 0.79 | LMNA (0.47) | LMNAMAPK1TSHRHTTKDM4C | |
| SCHEMBL11545347 | 0.78 | LMNA (0.49) | LMNAMAPK1TSHR | |
| SCHEMBL11521825 | 0.78 | LMNA (0.44) | LMNAMAPK1TSHRHTTKDM4C | |
| SCHEMBL11593788 | 0.76 | LMNA (0.48) | LMNAMAPK1TSHRHTTKDM4C | |
| SCHEMBL29557173 | 0.75 | LMNA (0.43) | LMNAMAPK1TSHRHTTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138589-A | CHEMICAL INTERMEDIATES FOR COMPOUNDS USED AS X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4069250-A | X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1978-01-17 | — | — | US | disclosed |